1c. A patient with persisting cough following viral upper respiratory tract infection.

Case history- A young lady presents with cough persisting for 13 days following recovery from a viral upper respiratory tract infection 20 days back.

What would you consider as differential diagnosis?

Acute bronchitis

Primary viral pneumonias

Post viral bronchial hyper reactivity

Precipitation of cough variant asthma

  • Acute bronchitisIt often follows acute coryza. Initially dry cough, then chest tightness, wheeze and breathlessness develop. Sputum is initially scanty or mucoid then becomes mucopurulent, more copious, and often blood-stained. Acute bronchitis may be associated with a pyrexia of 38-39°C. On auscultation of chest, wide spread rhonchi and crepitation are found. Spontaneous recovery occurs over a few days

 Treatment- Specific treatment rarely necessary in previously healthy individuals.

Amoxicillin 250 mg 8-hourly for 7 days

Cough may be eased by pholcodine 5-10 mg 6-8-hourly.

  • Primary viral pneumonias– may cause pneumonia commonly complicated by secondary bacterial infection which is treated as bacterial pneumonia.
  • Post viral bronchial hyperreactivity- Postviral bronchial hyperreactivity syndrome is a common complication of upper and lower respiratory tract viral infections. The respiratory symptoms closely resemble those of asthma (cough, wheeze and chest tightness), but they are present for only 3 weeks to 3 months following the acute viral infection.

Treatment- Bronchodilator such as beta 2 agonist inhaler (sulbutamol) and/or corticosteroid inhaler (beclomethasone) usually for 3 months.